Frequency of BK Polyoma Virus in Bladder Cancer
نویسندگان
چکیده مقاله:
The BK virus a member of the Polyomaviruses family was first isolated from the urine of the kidney recipient. Infection with this virus and infection usually occurs in childhood (5-9 years) but most of the time (90%) of sera are positive and without symptoms. Polyomaviruses including the BK virus have also been suggested to be a contributing factor to some cancers in humans such as brain tumors, bone tumors, Kaposi’s sarcoma, adrenal tumors, renal carcinoma, prostate cancer, urinary tumors, genital tumors and etc. however the topic still remains controversial. In this study, we report the presence of BK specific DNA sequences in bladder cancer by PCR and Nested PCR methods. Our study results confirmed the presence of BK in 13.7% of the samples.
منابع مشابه
Polyoma BK Virus: An Oncogenic Virus?
We report a case of a 65-year-old gentleman with a history of end stage renal disease who underwent a successful cadaveric donor kidney transplant four years ago. He subsequently developed BK virus nephropathy related to chronic immunosuppressant therapy. Three years later, misfortune struck again, and he developed adenocarcinoma of the bladder.
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عنوان ژورنال
دوره 14 شماره None
صفحات 0- 0
تاریخ انتشار 2020-06
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